TAMILNADU NURSING

OVERVIEW Thrombolytic therapy, also known as fibrinolytic therapy, is a cornerstone intervention in critical care for the rapid dissolution of intravascular thrombi. These agents restore perfusion to ischemic tissues and organs in time-sensitive, life-threatening conditions such as acute myocardial infarction (STEMI), ischemic stroke, and massive pulmonary embolism.             In critical care nursing, thrombolytic therapy demands precise assessment, vigilant monitoring, and rapid recognition of complications, especially hemorrhage.   DEFINITION       Thrombolytic therapy refers to the administration of pharmacological agents that activate the fibrinolytic system, leading to the breakdown of fibrin clots and restoration of blood flow.   PHYSIOLOGY OF COAGULATION AND FIBRINOLYSIS Coagulation Fibrinolysis Formation of a fibrin clot to stop bleeding ...