OVERVIEW Thrombolytic therapy, also known as fibrinolytic therapy, is a cornerstone intervention in critical care for the rapid dissolution of intravascular thrombi. These agents restore perfusion to ischemic tissues and organs in time-sensitive, life-threatening conditions such as acute myocardial infarction (STEMI), ischemic stroke, and massive pulmonary embolism. In critical care nursing, thrombolytic therapy demands precise assessment, vigilant monitoring, and rapid recognition of complications, especially hemorrhage. DEFINITION Thrombolytic therapy refers to the administration of pharmacological agents that activate the fibrinolytic system, leading to the breakdown of fibrin clots and restoration of blood flow. PHYSIOLOGY OF COAGULATION AND FIBRINOLYSIS Coagulation Fibrinolysis Formation of a fibrin clot to stop bleeding ...
Role of nurse in ICU Key Concept of Nursing Role: The role of a critical care nurse involves continuous monitoring, high-acuity clinical interventions, and rapid life-saving decision-making for patients facing life-threatening conditions . They manage advanced medical technology, administer complex therapies, and serve as the primary link between the patient, the medical team, and the family. Clinical Monitoring and Assessment Vitals : Tracks continuous ECG rhythms, arterial blood pressure, and oxygen saturation. Hemodynamics : Monitors central venous pressure (CVP) and pulmonary artery pressures. Neurology : Assesses neurological status using the Glasgow Coma Scale (GCS) regularly. Lab Work : Reviews arterial blood gases (ABGs), electrolytes, and metabolic panels constantly. Advanced Interventions and Technology Management Ventilation : Manages ventilator settings like ACV or PRVC, monitors PEEP, and performs endotracheal suctioning. Medications : Titrates p...